Interesting Nuedexta Off Label Uses Such as Parkinsons and MS

Off Label Uses of Nuedexta

Are you familiar with the combination drug Nuedexta? If so, then you may know someone who suffers from Pseudo-Bulbar Affect (PBA). This condition is relatively uncommon in the US, but it can have an enormous impact on the life of patients. It is characterized by uncontrollable episodes of laughing or crying, even if it doesn’t match how the person feels inside. Approximately 2 million individuals in the US suffer from PBA.

Nuedexta is the first-ever FDA approved treatment for PBA. It is a combination drug that includes dextromethorphan as well as the class I antiarrhythmic agent quinidine. Most patients with PBA also have some form of brain injury or other neurologic condition. Nuedexta has proven to be a lifesaver for them. However, it’s interesting to note that Nuedexta can also be used for treating other medical conditions.

Several studies have been conducted to test the efficacy of Nuedexta for treating other disorders. Early results appear to be very promising, with health experts recommending the use of Nuedexta even for patients who do not suffer from PBA. These off-label uses of the drug Nuedexta might scare off some people, with many fearing that the drug might cause certain side effects that will only worsen the condition.

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Alzheimer’s disease is one of the first medical conditions for which index is tested. Health experts conducted a randomized clinical trial to see how effective it will be for patients with Alzheimer’s and significant agitation. The group was divided in two. The first was provided with Nuedexta, while the other was given a placebo. It has been shown that Nuedexta was able to help patients manage their dementia symptoms better.

Similar results were seen when Nuedexta was given to people with bipolar disorder. All of the patients had some form of depressive symptoms for two years at a minimum. Following 90 days of treatment, signs of improvement were readily seen in the patients. Health experts, however, agree that more studies are necessary to have reliable evidence for proving the effectiveness of Nuedexta for treating bipolar disorder.

Additional OFF Label Uses of Nuedexta Drug

20-10 DMQ Nuedexta

Scientists also conducted a study involving patients with diabetic peripheral neuropathy. The goal was to evaluate the tolerability of the combination drug with diabetic neuropathy. Interestingly, the researchers found out that the drug leads to a significant reduction in pain while also improving sleep and overall quality of life. However, it’s important to note that for this study, in particular, a higher dosage was used than normal. This change in dosage could have had a large impact on the results of the research.

As you can see, there are plenty of Nuedexta off label uses, even for some of the more severe medical conditions. This doesn’t mean, however, that you should use it for the conditions are suffering from without the guidance of a medical professional. Also, you should make sure that you take the right dose of Nuedexta to avoid potential side effects. It’s important to keep in mind that despite the promising results of different studies, more evidence is needed to fully establish the effectiveness of Nuedexta off label uses when it comes to treating other medical conditions.

The medication used to make up the Nuedexta drug is in part what is used to also treat Parkinsons and MS.  While Nuedexta for Parkinsons is not a confirmed treatment for the disease, there is a clinical trial that was done that showed promising results of the use of the drug to treat the disease.

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Just like using any medication, be sure to work closely with your doctor so you can make sure that you are a perfect candidate for Nuedexta. There are instances in which the combination drug might cause more harm than good for your body. It can interact with other prescription medications you’re taking. Speak with your doctor first and ask how much to take daily and for how long. Following your physician’s instructions is always recommended to obtain optimal results.

Can Nuedexta Cause Weight Gain?

 

Nuedexta is a medication that is primarily prescribed for the treatment of pseudobulbar effect, a mental and mood disorder. It may occur for a wide variety of reasons, including individuals who have a stroke, ALS, and multiple sclerosis. The condition is often seen with uncontrollable and inappropriate crying or laughing outbursts.

Many doctors have also begun to prescribe Nuedexta for other reasons as well, such as for the treatment of Alzheimer’s disease. The two ingredients in this medication, dextromethorphan, and quinidine work together to treat the condition. Dextromethorphan operates in the brain, and quinidine works to help that medication. It is unsure how the medicine works, but it has been shown to relieve some of the symptoms.

Some people who had been prescribed Nuedexta or who have just started using it are wondering if it may cause weight gain. There are a number of side effects that may be associated with using this medication, including dizziness, vomiting, diarrhea, weakness, coughing and swelling in the extremities. Some people may also experience drowsiness. As is the case with any medication, you should always tell your doctor if you have any persistent or difficult to manage side effects to any medication.

is a side effect of Nuedexta weight gainSome people have also had a difficulty with weight gain when taking Nuedexta, but it does not seem to be a common problem. This may be an issue that is directly associated with taking this drug, but it may also be due to a combination of medications that are prescribed by your physician or perhaps even one of the other medications that you are currently taking. This is also a side effect that you should be discussing with your doctor if it occurs, as there may be ways to control the problem or to overcome it.

If you experience weight gain when taking Nuedexta, your doctor will help you to decide if you should continue taking it. It might be decided that the benefits of using this medication far outweigh any side effects that may be experienced. He may also have suggestions as to how you can lose weight as well, depending on your medical condition and some other factors.

Your doctor prescribed Nuedexta because he felt it was the best choice for you and that the benefits of using the drug would outweigh the potential for side effects. Weight gain is not considered to be a severe side effect, and it is associated with taking many different types of medicine. It is something that you can discuss with your doctor. Of course, if you have any serious side effects, such as signs of infection, jaundice, abdominal pain, dark urine, fainting, irregular heartbeat or severe dizziness, it should be discussed with your physician without delay.

Nuedexta is a medication that has helped many people with their symptoms. No drug is perfect in its ability to treat the symptoms in all individuals. Sometimes, it takes a few tries by your physician before the right medication or combination of drugs is discovered.

Can Nuedexta Cause Headaches?

It is estimated that approximately 2 million people in the United States are affected by a condition, known as the Pseudo-Bulbar effect. It results in bouts of inappropriate and uncontrollable crying or laughing. Typically, it is associated with a brain injury or other conditions, such as Parkinson’s disease, Alzheimer’s, Lou Gehrig’s disease, stroke and multiple sclerosis. Your doctor may prescribe Nuedexta to treat the symptoms of this condition.

Headache from Nuedexta?

Many people who have been prescribed Nuedexta are wondering if headaches are a side effect of the medication. Other individuals who may already be taking the drug and have a headache wonder if it is associated with the medication or if it is just a random event. Taking a closer look at the side effects can help answer that question and see if it is something that should be discussed with your physician.

Headache with NuedextaThere are some side effects that may be associated with using Nuedexta, including dizziness, diarrhea, vomiting, coughing, weakness, and drowsiness. Although headaches are not typically listed as one of the primary potential side effects of this drug, it has been reported by some individuals. According to at least one study, approximately 13% of those who use Nuedexta report a headache as a side effect. Does that mean that it is likely that you are going to have this problem as well?

Before the time that your physician prescribes Nuedexta, he will discuss your current medical condition and any other medications that you are using. Knowing this information can help to reduce the possibility of side effects, including a headache. At times, drug interactions can lead to unexpected side effects, which is something that the doctor is trying to avoid by having a list of medications that you are taking. The same can also be true for your current medical condition, as there may be certain factors that could increase your possibility for headaches.

Another issue that may be associated with using Nuedexta are some severe drug interactions. These are also things that need to be checked on prior to the time that you are provided with a prescription. For example, Nuedexta may not work well with certain tricyclic antidepressants, digoxin or aliskiren. There may also be other medications that affect how quinidine, one of the medications in Nuedexta, is removed from the body. Using this drug along with a MAO inhibitor could cause potentially fatal drug interactions.

One of the most important things to keep in mind is that all side effects should be discussed with your physician if they become a problem. Regardless of whether it is a headache, nausea or any other problem you are experiencing, your doctor may be able to come up with a solution to reduce the issue or to remove it altogether. Headaches are not typically a severe side effect, but if they should happen become serious, you should seek medical attention without delay. More than likely, you will be able to use Nuedexta without headaches, but you should always watch for the potential problem.

Nuedexta and MS: Important Facts

Using Nuedexta to treat MSNuedexta is an effective drug that is used to manage uncontrollable emotional outbursts in people who suffer from multiple sclerosis (MS). The drug was developed by Avanir Pharmaceuticals and was first approved in the United States in 2010. The drug has been found effective in reducing the number of episodes of uncontrollable emotional expression. In fact, uncontrollable bouts of laughing or crying affect approximately 10% of patients who are suffering from MS. It is something that is quite distressing and embarrassing for people who are living with MS and their families and carers. That’s where Nuedexta comes in handy. This article provides information on the importance of Nuedexta in treating the symptoms of MS.

The symptoms of multiple sclerosis (MS) are variable and unpredictable most of the time. In fact, no two persons will have the same symptoms. On the other hand, each patient’s symptoms could fluctuate or change over time. While one patient may experience only a symptom or two, another patient will experience many other symptoms in the process. Most of the symptoms associated with MS could be easily managed with the right kind of medication.

Managing MS is considered an ongoing process. Hence, it is never too soon or too late to think about accessing the right type of treatment for your condition. Knowing what to look for and finding the right health care professional are important steps in treating the symptoms associated with MS effectively.




Uncontrollable bouts of crying and laughing episodes related to MS affects about 10% of patients who are living with multiple sclerosis. This condition is also known as the Pseudobulbar Affect or Affective Release. The condition is thought to have come from MS-related damage to the nerves in the brain that controls the expression of emotions. Nuedexta is an effective treatment for this condition. That’s why your doctor would prescribe this medication to manage such uncontrollable emotional outbursts in you.

Nuedexta contains a combination of quinidine and dextromethorphan. Dextromethorphan usually affects the brain signals that would trigger a cough reflex. That’s why it is used as a cough suppressant. On the other hand, quinidine would affect the way your heart beats. It is commonly used in patients who suffer from certain heart rhythm disorders. The combination of these ingredients has resulted in an effective medication to treat some of the symptoms of MS.

You should take Nuedexta exactly as prescribed by your health care provider. Follow the directions of your doctor and don’t take the medication in smaller or larger amount. You should not take medicine longer than the recommended period. The medication is usually prescribed as one capsule a day for the first seven days and one capsule every twelve hours after that. Don’t take more than two capsules of Nuedexta within a 24-hour period. You can take the capsule with or without food. Your doctor may require to check the progress and adjust the dosage accordingly. That is why it is important that you see your doctor while taking the medication. You should take the dose as soon as you remember in case you have missed a dose. Skip it if it is almost time for the next dose. These are critical things to consider when taking Nuedexta for your MS condition.




In conclusion, multiple sclerosis has many symptoms including uncontrollable emotional outbursts such as uncontrollable bouts of laughing and crying. Nuedexta is an effective drug prescribed to treat these symptoms of MS. Your doctor is the best person to decide on the right prescription for your condition. The above article provides information on what you should know about Nuedexta and MS.

A Look At Nuedexta, Avanir Pharmaceuticals

Avanir Pharmaceuticals makers of Nuedexta
Image courtesy of https://americanmigrainefoundation.org/american-registry-migraine-research/

PseudoBulbar Affect (PBA) affects approximately 2 million people within the United States and much more worldwide. It is a neurological condition and is often associated with different types of brain injuries, including those that occur with a stroke, multiple sclerosis, Parkinson’s disease and Alzheimer’s. The most common symptom of PBA is an uncontrolled and inappropriate laughing or crying. The only FDA approved treatment for the symptoms of PBA is Nuedexta.

Nuedexta contains two primary ingredients, dextromethorphan, and quinidine. These medications have been used separately for the treatment of other conditions, but when used together, they may be able to help reduce or eliminate the symptoms of PBA in some individuals. In clinical trials, it has been shown that it reduced the involuntary laughing and crying that is associated with the condition. In fact, in a 12-week study, patients experienced, on average, 82% fewer episodes of PBA. These results are promising, considering that a placebo only led to a 45% reduction. Over half of the patients had eliminated PBA episodes by the final two weeks of the study.

Avanir Pharmaceuticals is a biopharmaceutical company that is primarily focused on producing medicines that help individuals who have disorders of the central nervous system. One of those medications, available by prescription only, is Nuedexta. In October 2010, Avanir Pharmaceuticals obtained approval for Nuedexta from the US Food and Drug Administration (FDA). Since then, they had also received marketing authorization from the European Union in 2013. As of this date, it is approved for use in the United States, European Union, Norway, and Iceland.

The two different medications in Nuedexta work in conjunction with each other to reduce the symptoms of PBA. Dextromethorphan is commonly prescribed as a cough suppressant on its own. It affects the brain cycles that trigger the reflex of coughing. It is not effective at treating coughing associated with asthma, smoking or emphysema. Quinidine is commonly prescribed on its own as an antiarrhythmic medication to treat conditions such as atrial flutter and atrial fibrillation. It may also be used for the treatment of malaria.




It’s not entirely understood how the combination of medications works to reduce the symptoms of PBA. It is thought, however, that it regulates excitatory neurotransmissions with the Sigma-1 receptor antagonist activity. It may also have an effect on the NMDA receptor antagonist activity as well. This effect is thought to be due to the actions of Dextromethorphan, with Quinidine helping to reduce how quickly the Dextromethorphan breaks down in the brain.

Nuedexta was given FDA approval after a phase III clinical trial. This clinical trial enrolled patients who had multiple sclerosis or Lou Gehrig’s disease. Over the course of 12 weeks, they were either provided with Nuedexta or a placebo. The study was conducted to determine if the crying and laughing episodes could be reduced. The study concluded that those events were reduced significantly by the group that used Nuedexta in comparison to those that used the placebo. A similar study was performed for CHMP approval.

When the drug was first introduced in 2006, the FDA did not give its approval. They felt, at the time, that there were some issues associated with heart rhythm safety. The concern was primarily over quinidine and the possibility that it led to QT prolongation, which could be linked to an increased risk of heart attack. Nuedexta was then reformulated so that a lower dose of quinidine was included. New studies were conducted so that approval could be received.

Although Nuedexta has been prescribed for use in those with PBA, it may also be prescribed for other conditions as well. Some physicians are giving the prescription for agitation associated with Alzheimer’s disease, and it may also be prescribed for severe depression as well. The doctor can make the determination why this medication should be prescribed.

Nuedexta has shown real promise in helping individuals with a critical condition to lead a life that is free of the symptoms. It may also be beneficial for other conditions as well. Talk to your doctor about the possibility of using this medication and discuss your current medication usage and medical history. You may just find that it is the best option for you.

Looking At The Differences Between Nuedexta And Zoloft

When it comes to medication, it’s important to remember that the “one size fits all” philosophy isn’t always going to hold true. One person may have a great experience with a particular medication, while another person may have some issues.

If you’re concerned about this, you should talk to combination of Nuedexta and zoloft medicationyour doctor about any medication before you start taking it. You should also try to speak to people that have taken this drug. Have conversations with them so that you can learn what you should expect.

If you look at the differences between Nuedexta and Zoloft, for example, you’ll be able to learn a great deal.

Both Medications Treat A Number Of Conditions

Neither medication is used to treat one condition exclusively. Both medicines are used to treat a variety of conditions.

If you have depression, you could be offered many medications. The same goes for children with autism or adults with ADHD. There are plenty of ways to treat these conditions and both of these medications have been used in a number of ways.




These Medications Are Primarily Used To Treat Different Conditions

Nuedexta was designed to treat the symptoms of Pseudobulbar Affect (PBA), a secondary effect of other neurological conditions such as dementia, Amyotrophic lateral sclerosis (ALS), and Multiple sclerosis (MS).  Although it has been employed in other ways since then, it’s clear that this is the primary purpose of this drug.

Zoloft was created to treat the symptoms of depression. Although doctors prescribe it for people with different conditions, this is still its most common use.

These are different types of medications, and they are often used to treat different things.

They Have Different Side Effects

One of the nice things about both of these medications is that the majority of people that take them don’t experience severe side effects. However, that doesn’t mean that the list of side effects that these medications can cause are identical.

You shouldn’t assume that the side effects for both of these medications are the same. They can cause different reactions for different people. If you aren’t familiar with the side effects for one of these drugs, you should read up on them so that you can learn more.

The Cost Isn’t The Same

The price that people will pay for these medications is going to vary based on the insurance policy that they have. That said, they don’t have the same cost. It’s easier to purchase a cheaper version of Zoloft, especially when you are willing to try the generic version of this drug.  There is no generic version of the Nuedexta drug.

If savings are important to you, you should talk to your doctor about the most affordable medication options. They should be able to help you find a drug that will treat your condition without requiring you to spend a fortune.

They Can Be Combined

Doctors tend to be careful about combining medications. The way a medicine works can change when it is combined with something else.




Studies have suggested that these drugs can be safely combined. However, that doesn’t mean that you can take them together without talking to a doctor. You should always be very careful about mixing medications. You should also talk to a physician before you start taking something new. If a different doctor has prescribed a medication to you, you should speak to them about what you are currently taking.

Are you interested in learning more about the differences between Nuedexta and Zoloft? If you want to read up on these drugs, you’ll find a wealth of information. You should research these medications on your own time, but you should also talk to a doctor about them. A physician will be able to give you the information you won’t be able to find online.

Zoloft drug

Should You Use Nuedexta To Treat ALS

If you or a loved one is suffering from ALS, you are probably looking for medications that will help you to manage your symptoms. You may want to talk to your doctor about Nuedexta. While this medication has traditionally been used to help people with bouts of uncontrollable laughter, it has proven effective for treated some symptoms.

Should you use this medication? Here are a few of the benefits that it offers.

It’s The Only Medication That Is FDA Approved To Treat PBA

If you have issues with PBA, and you are looking for treatment, this is the medication that you are going to want to look at. At the time of writing, it is the only drug that has been approved by the FDA for this use.

While PBA symptoms can be very similar to depression symptoms, the two have very different causes. You can’t treat PBA like you would treat depression. You need to use a drug that will be a better fit for your specific issues.




It Was Developed By A Neurologist

A lot of medications were created by someone that has a limited understanding of neurology. However, that isn’t true of Nuedexta. This particular drug was designed by a neurologist. This is why it can do things that a lot of other medications can’t.

The drug was created by Dr. Richard A. Smith, who has worked with the Center for Neurologic Study for quite some time. He has a lot of experience with ALS patients, and he has a better understanding of their needs then many of the people developing pharmaceuticals do.

We Have A Lot Of Information About How It Works

There are some drugs on the market that are still very experimental. We only have a limited amount of information about how they work. Luckily, this isn’t true when it comes to Nuedexta. A number of studies have been conducted, and we know exactly how it impacts the brain.

This drug impacts sigma-1 and NMDA receptors in the brain. It has had a positive effect for a lot of people, and it works very quickly.

It Is Supported By Organizations And Doctors Alike

A number of respected doctors have spoken out in favor of this wonderful medication. ALS Worldwide has also sung the praises of this medicine. It’s done a lot of good, and that means that it has received a ton of support.

People aren’t usually willing to get behind medications like this unless the medications have delivered results. This medication has helped many, many patients, and it will help even more patients in the future.

It Has Minimal Side Effects

Obviously, side effects are always going to be a concern with medication. This is particularly true for people with serious conditions like ALS. Side effects can be devastating when you are already trying to cope with a serious condition. This drug isn’t completely free of side effects; some patients have encountered minor side effects. With that said, the effects aren’t particularly severe.




You should speak to your doctor about the side effects. You may be pleasantly surprised when you realize how few side effects this medication has. A large number of people have been able to take it without a problem.

Ultimately, you and your doctor are going to have to decide whether or not you should use Nuedexta to treat ALS. With that said, you should definitely bring this medication up at your next doctor’s visit. Talk about the benefits of this medication and see what your doctor thinks about it. They may wind up writing you a prescription.

Possible PBA Treatment Nuedexta Drug Interactions

As a patient starting a new medication, it is always important to be aware of possible interactions and effects that may occur. This awareness is of particular importance when dealing with any drugs that can affect your mental health. This reason is why talking to your doctor before you start any medication, even over the counter while taking medication for depression or neurological issues is critical. You should also be careful drinking alcohol and cautious of any changes to your routine.

For Nuedexta, there are a large number of possible interactions from the drug, and many of them may make the symptoms that you are trying to treat much worse over time. These interactions are why people often feel that this treatment isn’t working for them, or why they have related feelings of being tired, sluggish, emotionally worn out, or having symptoms that are over the top.

Regarding foods, people taking Nuedexta should avoid eating grapefruit or drinking the juice when they are on the medication. The juice of this fruit was found to make the drug take longer to work entirely. In some people it even made it less effective over time, causing them to suffer more. No other types of citrus or food interactions were observed.

Alcohol was also found to have an adverse effect on people taking this drug. Patients who drank while on Nuedexta medication found themselves uncontrollably sleepy were unable to concentrate even on basic things and had increased levels of dizziness including when sitting down. Other people concluded that they were unable to think clearly at all, making them disoriented and feeling lost. Many others experienced impaired judgment that was detrimental to them, their health, or to others around them.

There have also been reported interactions with different levels of over the counter vitamins and herbs that were not approved for use with the medication. These are too numerous to list, but the symptoms included everything from breaking out in hives to an increase in multiple sclerosis progression. Most of these interactions were solved by talking with a doctor and altering or stopping the supplemental medication that was being taken at that time.




Other people found that Nuedexta increased the amount of time that different drug stayed in their body, making it more or less effective. This increase meant that they needed to adjust the dosage that they were taking to ensure that they were not damaging their organs, prolonging their effects, or mixing medications that should be kept separate. This interaction was positive in a few cases where it allowed patients to take less medication for better results.

Still, other interactions include medications causing the usage of Neudexta to be less effective or to take longer to achieve the desired effect. These are similar to the grapefruit juice effect mentioned earlier, and avoidance should be the effort at all costs.

No matter what you are thinking of taking while on the Nuedexta drug, you will need to talk with your doctor to ensure safety and that it will not be detrimental to your health. Be sure to bring any over the counter medication with you to your appointment.

drug interactions of Nuedexta

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